Bis(hydroxyl)-terminated PLA-PEG-PLA triblocks | Nasal packing

After sinus surgery, it is important to use nasal packing to help control bleeding and provide support to separate tissue and structure at the surgical site. The device comprises bis(hydroxyl)-terminated PLA-PEG-PLA. This device functions to fill nasal/sinus cavities following surgery or trauma and to keep mucosal surfaces separate during the healing process.

The hydrogel polymer is an application-tailored PLGA-PEG-PLGA triblock polymer

The hydrogel polymer is an application-tailored PLGA-PEG-PLGA triblock polymer.
The polymer molecule exhibits a hydrophilic core region and hydrophilic ends. An aqueous solution of this polymer is reverse thermosensitive, meaning it is fluid and injectable at room temperature and will rapidly form a hydrogel at body temperature (e.g. after subcutaneous injection).

The polymer is biodegradable due to the instability of ester bonds in the aqueous physiological environment. This process continues at a slow rate and will eliminate the hydrogel from the body in several weeks in a non-toxic way.

https://nomismahealthcare.com/catalog/polylactide-co-glycolide-block-polyethylene-glycol-block-polylactide-co-glycolide-PLGA-PEG-PLGA-2/