Blog
Introducing the Future of Dental Care: PLGA Encapsulation of Lidocaine
At Nomisma Healthcare Pvt. Ltd., we are pushing the boundaries of dental technology with our advanced PLGA (Poly(lactic-co-glycolic acid)) polymers, specifically designed for encapsulation of lidocaine in dental cosmetic procedures. 🔬 Why Choose PLGA for Lidocaine...
Revolutionizing Triple Chemotherapy with PEG-PLGA Nanoparticles
At Nomisma Healthcare Pvt. Ltd., we are pushing the boundaries of dental technology with our advanced PLGA (Poly(lactic-co-glycolic acid)) polymers, specifically designed for encapsulation of lidocaine in dental cosmetic procedures. 🔬 Why Choose PLGA for Lidocaine...
mPEG-PLA Polymer: A Key Component in Nanoparticle Drug Delivery
The landscape of drug delivery systems has evolved significantly in recent years, with nanotechnology playing a pivotal role. One of the noteworthy innovations in this space is Cynviloq, a nanoparticle formulation of the chemotherapeutic agent paclitaxel. At the core...
Introduces Sterile PLGA 50:50 for Treptorelin Depot Formulation
Nomisma Healthcare is excited to announce the introduction of our innovative Sterile PLGA 50:50, designed specifically for use in Treptorelin Depot formulations. This advancement promises to enhance the delivery and efficacy of Treptorelin, providing substantial...
Webinar on Revolutionizing Oncology PLGA Polymer in Parenteral Formulation
Webinar on Revolutionizing Oncology: PLGA Polymer in Parenteral Formulation
Leuprolide Depot – Long-acting injectable formulation technologies
Double Emulsion –solvent extractionAn aqueous solution of the peptide (which may contain excipients such as gelatin) is first emulsified in a polymer vehicle where the polyesters have been solubilized in an organic solvent (generally dichloromethane or ethyl acetate)....
Bioresorbable solid implants for peptides : Goserelin acetate
Hot-melt extrusion(HME) The molecule in its solid state is mixed with the thermoplastic polymer that is heated (at a temperature above the PLGA/PLA glass transition temperature) and forced through a small orifice called a die to form a rod with a defined diameter....
Initial burst release
Leuprolide acetate which is a highly active agonist of luteinizing hormone–releasing hormone (LH-RH) potently inhibits their secretion in the pituitary gland and it is useful in the treatment of hormone-dependent diseases in males and females. To eliminate the...
Factors affecting drug release
The drug release from the Leuprolide acetate depot mainly depends on the hydrolysis or degradation of PLGA (Poly lactic Co Glycolic acid) polymer involving diffusion and/or erosion either from its surface or from the mass. The initial burst also depends upon the drug...