Breakthrough in Bone Healing: RFS Fixation System with PLGA 85:15 by Nomisma Healthcare

The RFS Fixation System: Precision Solutions with PLGA 85:15 by Nomisma Healthcare

Introduction

  • The RFS Fixation System is a resorbable solution for orthopedic and maxillofacial surgeries.
  • Includes screws and pins for stabilizing bones during healing.
  • Resorption period: 12 to 18 months, eliminating the need for secondary surgeries.

PLGA 85:15: The Core Material

  • Nomisma Healthcare’s PLGA 85:15 is the core material for the RFS system.
  • Composition: 85% lactic acid (LA) and 15% glycolic acid (GA).
  • Offers precise degradation and robust mechanical support.

Key Features of PLGA 85:15

  1. Degradation Rate
    • Degrades within 12 to 18 months.
    • Aligns with bone regeneration processes.
    • Breaks down into non-toxic byproducts like water and carbon dioxide.
  2. Molecular Weight (Mw)
    • Ranges between 50,000 to 70,000 Daltons.
    • Balances mechanical strength and controlled degradation.
  3. Intrinsic Viscosity (IV)
    • Optimal range: 0.4 to 0.6 dL/g.
    • Ensures suitable chain length for mechanical and degradation properties.
  4. End Group Termination
    • Ester-terminated PLGA is preferred.
    • Slower hydrolytic degradation maintains mechanical integrity longer.

Applications in the RFS System

RFS Screws

  • Stabilize bone fragments in fractures, osteotomies, and reconstructive surgeries.
  • Provide mechanical support during the initial healing phase.

RFS Pins

  • Ideal for minor fractures and non-load-bearing applications.
  • Ensure secure stabilization with flexibility.

Why Nomisma’s PLGA 85:15?

  • Precision: Consistent molecular weight and viscosity for predictable performance.
  • Safety: High biocompatibility, adhering to global implant standards.
  • Customization: Tailored properties for diverse medical applications.

Research Reference

Conclusion

  • The RFS Screw and Pin System exemplifies innovation in resorbable medical implants.
  • Backed by Nomisma Healthcare’s PLGA 85:15.
  • Offers exceptional degradation properties and mechanical reliability, advancing surgical outcomes and patient care.