mPEG–PLA Copolymer (mPEG 2000 Da – DL-PLA 1700 Da)

mPEG–PLA (methoxy poly(ethylene glycol)–poly(D,L-lactide)) is a biodegradable, amphiphilic block copolymer widely used in advanced pharmaceutical drug-delivery systems. The combination of mPEG 2000 Da and DL-PLA 1700 Da enables self-assembly into stable micelles, improved drug solubilization, and controlled release behavior.

The PEG block provides hydrophilicity and stealth characteristics, while the DL-PLA block forms a biodegradable core suitable for encapsulating hydrophobic drugs and peptides.

• Amphiphilic block copolymer suitable for micelle and nanoparticle formation
• Biodegradable and biocompatible polymer system
• Enhances solubility of poorly water-soluble drugs
• PEG shell reduces protein adsorption and immune clearance
• DL-PLA block enables controlled and sustained drug release
• Suitable for parenteral and injectable formulations

• Polymeric micelles for drug solubilization
• Nanoparticle-based drug delivery systems
• Long-circulating injectable formulations
• Peptide and small-molecule delivery
• Controlled-release and nano-depot systems
• Research and development of complex generics

mPEG–PLA is preferred in pharmaceutical and biomedical applications due to its ability to combine PEGylation benefits with biodegradable polyester chemistry. The PEG segment improves circulation half-life, while the DL-PLA block provides predictable degradation and controlled drug release, making it suitable for oncology, peptide, and injectable nano-formulations.

Supplied under controlled conditions with batch-wise Certificate of Analysis (COA). Available in gram to kilogram quantities. Custom molecular weights and block ratios can be provided on request.