Chemical Structure



CAS Number 26680 10 4
Systematic Name: Propanoic acid, 2-hydroxy-, homopolymer, PDLLA
Molecular Formula: (C3H6O3)x
EPA Registry Name: Polylactic acid
Former CAS Number(s) 1104201-86-6, 31587-11-8, 1148011-07-7, 947236-64-8, 1384255-85-9
Substance Type: DL-PLA | DL 100-2A | Inherent Viscosity : 0.15 - 0.30 dL/g | Acid terminated  |L- Lactide : D-Lactide 50:50 | Mw 10-25 kDa Biodegradable Polymer, Excipient, Non-Active pharmaceutical ingredient, Nanoparticles.
Synonym:  PLA, Poly(D,L-lactide) acid terminated, Poly(DL-lactide), acid terminated, PDLLA

Qualitative Analysis

Appearance White to tan colored solid powder
Inherent viscosity (IV) 0.15 - 0.30 dL/g, in chloroform(25 °C)
L-Lactide  50% ( ± 2%)
D-Lactide 50% ( ± 2%)

Quantitative Analysis

Assay ≥ 98 %
Residual monomer ≤ 0.2 %
Residual solvent Complies
Heavy metal Complies


Poly(D, L-lactide)- DL 100-2A (DL-PLA) has been one of the most attractive Biodegradable and biocompatible polymers used to fabricate devices for diagnostics and other applications of clinical and basic science research, including vaccine, cancer, cardiovascular disease, and tissue engineering. In addition, DL-PLA and its copolymers are Essential in designing nanoparticles with desired characteristics such as biocompatibility, biodegradation, particle size, surface properties, drug release, and targetability and exhibit a wide range of erosion times. DL-PLA has been approved by the US FDA for use in drug delivery complex formulation and biodegradable orthopedic Medical implants.   Reference : [1] Chen G, Ushida T, Tateishi T. Scaffold design for tissue engineering. Macromol Biosci 2002;2:67–77. [2] Nair LS, Laurencin CT. Biodegradable polymers as biomaterials. Prog Polym Sci 2007;32:762–798. [3] Peter SJ, Miller MJ, Yasko AW, Yaszemski MJ, Mikos AG. 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