PLGA Applications

Nomisma offers bioresorbable / biodegradable polymers as an excipient in parenteral controlled release drug delivery systems & raw material for medical devices

MORE THAN 25 YEARS OF EXPERIENCE IN THE FIELD OF BIORESORSABLES POLYMERS

Drug Delivery

Drug formulators are using self-absorbable polymers to create drug delivery systems that improve the patient’s health. Flexibility, convenience and better compliance to meet patient needs can all be incorporated into the system design process involving the use of Proteins, vaccines, and other biological molecules. Scientists can use our polymer to develop & manufacture strategies of controlled release injectable depots, micro/nanoparticles, and solid implants. API together with polymer and solvent is mixed to form a gel which is injected into the patient so that the drug can release as per necessity.

  • Poly (D, L-Lactide) (PDLLA)
  • Poly (D, L-Lactide-co-Glycolide) (PLGA)
  • Poly (D, L-Lactide-co-Glycolide-co-PEG) (PLGA-PEG-PLGA)

Medical Devices

Bioresorbable Polymers are valuable additives inside the design and manufacture of Medical Devices such as: Screws, Plates and Bone regeneration scaffolds, Staples and Sutures, Neural conduits, Hernia meshes, Stents, Device coatings, Dental and Ophthalmic treatments

  • Poly(L-Lactide) (PLLA)
  • Poly(ɛ-Caprolactone) (PCL)
  • Poly(L-Lactide-co-ɛ-Caprolactone) (PLCL)
  • Poly(Glycolide) (PGA)

Poly (DL-Lactide-co-Glycolide) PLGA

Synonym: PLGA, Poly(D,L-lactide-co-glycolide) ,Poly(DL-lactide-co-glycolide), PGLA

CAS Number: 26780-50-7

The ratio of Lactide and Glycolide: PLGA 50:50, PLGA 75:25, PLGA 85:15, PLGA 55:45, PLGA 45:55, PLGA 55:45 Star Glucose, PLGA 90:10, PLGA 10:90, Or any custom ratio of La and GA.

Inherent viscosity (IV.) range: 0.15 dg/L to 2.3 dg/L

End Group: Acid terminated, Ester terminated, Hydroxy terminated, etc.

Poly (D, L-Lactide) (PDLLA)

Synonym: Polylactic acid, Poly(L-lactide), Poly(D,L-lactide) , Poly(D-lactide), PLA, PLLA, PDLA, PDA, PDLLA etc.

CAS Number: 33135-50-1

The ratio of L-Lactide and D-Lactide: PLLA 100: 00, PDLLA 50:50, PDLLA 75:25 ,PDLLA25:75 , PDLA 00:100 etc.

Inherent viscosity (IV.) range: 0.15 dg/L to 2.3 dg/L

End Group: Acid terminated, Ester terminated, Hydroxy terminated, etc.

Other Polymers

All bioresorbable polymers can be customized with defined chemical structures/composition, molar mass (molecular weight or inherent viscosity) & selective terminal end groups. some are as Poly(D, L-Lactide-co-Glycolide-co-PEG) (PLGA-PEG-PLGA), Poly(ɛ-Caprolactone) (PCL), Poly(L-Lactide-co-ɛ-Caprolactone) (PLCL), Poly(Glycolide) (PGA), PLGA-NH2, M-PEG-OH, M-PEG-PLGA, M-PEG-NH2.

Recent Posts for PLGA Applications

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PLGA, a smart polymer for Drug Delivery System

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