PLGA 50:50 | DLG 50-8A

PLGA 50:50 | DLG 50-8A is an acid terminated Pharma / Medical Grade copolymer of DL-lactide and Glycolide in a 50:50 molar ratio and with an inherent viscosity midpoint of 0.8 dl/g. It is supplied in the form of white to light tan micronized powder. DLG 50-8A is primarily used for drug delivery applications and is suitable for all commonly used formulation techniques.

CAS Number:
26780-50-7

Molecular Formula:
(C3H4O2)m x (C2H2O2)n

Synonyms:
PLGA, Poly(D,L-lactide-co-glycolide) acid terminated, Poly(DL-lactide-co-glycolide), acid terminated

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Additional information

CAS Number

26780-50-7

Former CAS Number(s)

107760-14-5, 119652-89-0, 1255770-56-9, 130953-65-0, 31213-75-9, 339986-68-4

EPA Registry Name

The polylactic acid-polyglycolic acid copolymer

Substance Type

Acid terminated, Biodegradable Polymer, Excipient, Inherent Viscosity: 0.65-0.90, Lactide : Glycolide 50:50, Mw 80-130 kDa, Nanoparticles, Non-Active pharmaceutical ingredient, PLGA 50:50

Synonym(s)

1, 4-Dioxane-2, 5-dione copolymer, 5-dione-1-DL-3, 6-dimethyl-1, Glycolide – lactide copolymer, Glycolide-DL-lactide copolymer, Glycolide-DL-lactide polymer, Lactide – glycolide copolymer, Lactomer, Poly(DL-lactide-co-glycolide), Poly(glycolide – lactide), Poly(glycolide-co-lactide), Polyglactin

Applications

Drug delivery formulations

Appearance

Solubility

,

FT NMR (PROTON)

FT IR

Lactide by NMR

Glycolide by NMR

Viscosity (1% in CHCl3)

Residual monomer DL-Lactide

Residual monomer Glycolide

Residual solvent acetone

Residual solvent toluene

Total Residual solvent

Acid number

Heavy metal

PS equivalent mol. weight Mw by GPC

Sulphated Ash

TAMC

TYMC

Bacterial Endotoxins

Self life

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