PLGA 55:45 | DLG 55-4G

DLG554G | PLGA 55:45 star Glucose is a Pharma / Medical Grade copolymer of DL-lactide and Glycolide in a 55:45 molar ratio having an inherent viscosity midpoint of 0.45 dl/g. It is supplied in the form of white to light tan micronized powder. DLG554G | PLGA 55:45 is primarily used for the Octreotide Depot microsphere and other drug delivery applications.

 

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Description

CAS Number26780-50-7
Systematic Name1, 4-Dioxane-2, 5-dione-1-DL-3, 6-dimethyl-1, 4-dioxane-2, 5-dione copolymer, Glycolide – lactide copolymer, Glycolide-DL-lactide copolymer, Glycolide-DL-lactide polymer, Lactide – glycolide copolymer, Lactomer, Poly(dl-lactide-co-glycolide), Poly(glycolide – lactide), Poly(glycolide-co-lactide), Polyglactin
Molecular Formula((C3H4O2)m x (C2H2O2)n x Glucose
EPA Registry Name 55:45 Poly(DL-lactide-co-glycolide), D-glucose
Former CAS Number(s):107760-14-5, 119652-89-0, 1255770-56-9, 130953-65-0, 31213-75-9, 339986-68-4
Substance TypePLGA 55:45 | Inherent Viscosity: 0.40-0.60 | D-Glucose terminated | Lactide : Glycolide 55:45 | Mw 40 kDa
Biodegradable Polymer, Excipient, Non-Active pharmaceutical ingredient, Nanoparticles.
SynonymPLGA, Poly(D,L-lactide-co-glycolide) acid terminated, 55:45 Poly(DL-lactide-co-glycolide), D-glucose
ApplicationsDrug delivery formulations, Octereotide Depot 1 month

Additional information

Appearance

Solubility

FT NMR (PROTON)

FT IR

Lactide by NMR

Glycolide by NMR

Viscosity (1% in CHCl3)

Residual monomer DL-Lactide

Residual monomer Glycolide

Residual solvent acetone

Residual solvent toluene

Total Residual solvent

Acid number

Heavy metal

Tin

PS equivalent mol. weight Mw by GPC

Sulphated Ash

TAMC

TYMC

Bacterial Endotoxins

Self life

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