PLGA 55:45 | DLG554Glu

DLG554Glu is Pharma / Medical Grade branched copolymer made by ring-opening polymerisation of DL-lactide and Glycolide in a 55:45 molar ratio and with an inherent viscosity an inherent viscosity ranging from 0.45 dl/g to 0.60 dl/g.

It is supplied in the form of white-coloured lyophilized powder.

Primarily utilized in parenteral formulations for Octreotide depot preparation. Its applications extend to tissue engineering, nanoparticle formulation, and microsphere formulation, among other diverse uses.

CAS Number:
26780-50-7

Manufacturing Process:
Ring-Opening

Molecular Formula:
(C3H4O2)m x (C2H2O2)n

Synonyms:
PLGA, Poly(D,L-lactide-co-glycolide) star glucose

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Additional information

Former CAS Number(s)

107760-14-5, 119652-89-0, 1255770-56-9, 130953-65-0, 31213-75-9, 339986-68-4

Synonym(s)

1, 4-Dioxane-2, 5-dione copolymer, 5-dione-1-DL-3, 6-dimethyl-1, Glycolide – lactide copolymer, Glycolide-DL-lactide copolymer, Glycolide-DL-lactide polymer, Lactide – glycolide copolymer, Lactomer, Poly(DL-lactide-co-glycolide), Poly(glycolide – lactide), Poly(glycolide-co-lactide), Polyglactin

Substance Type

Biodegradable Polymer, D-Glucose terminated, Excipient, Lactide : Glycolide 55:45, Mw 40 kDa, Nanoparticles, Non-Active pharmaceutical ingredient, PLGA 55:45, Inherent Viscosity 0.45 – 0.60 dL/g

EPA Registry Name

55:45 Poly(DL-lactide-co-glycolide), D-glucose

Appearance

Solubility

,

FT NMR (PROTON)

FT IR

Lactide by NMR

Glycolide by NMR

Viscosity (1% in CHCl3)

Residual monomer DL-Lactide

Residual monomer Glycolide

Residual solvent acetone

Residual solvent toluene

Acid number

Heavy metal

Tin

PS equivalent mol. weight Mw by GPC

Sulphated Ash

TAMC

TYMC

Bacterial Endotoxins

Self life

End Group

Glucose

Molecular Weight

32,000 – 64,000 da

Ratio

lactide:glycolide (55:45)

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