Poly(L-lactide-co-ε-caprolactone) | PLCL 70:30 is an Ester terminated Medical Grade copolymer of L-lactide and ε-caprolactone with an inherent viscosity midpoint of 1.2 dl/g.
Product Description
| CAS Number | 65408-67-5 |
| Systematic Name | (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione, polymer with 2-oxepanone, PLCL |
| Molecular Formula | [(C6H8O4)x(C4H4O4)y]y |
| EPA Registry Name | L-lactide/Caprolactone copolymer |
| Substance Type | PLCL 70:30 | L10012A | Inherent Viscosity : 1.2 - 1.8 dL/g | Ester terminated Biodegradable Polymer, Excipient, Non-Active pharmaceutical ingredient, Nanoparticles. |
| Applications | Biodegradable, biocompatible, and bioresorbable copolymer composed of L-Lactide and ε-Caprolactone. This semi-crystalline material has been used in the fabrication of research medical devices and research tissue engineering solutions, such as orthopedic or soft tissue fixation devices. Degradation of these materials has been thoroughly studied and has been shown to be safely resorbed by the body after implantation. Modification of molecular weight and polymer composition allows for control of the degradation rate and mechanical stability of the polymer. |
Specification
| Appearance | White to light tan |
| FT NMR (PROTON) | Should comply |
| Lactide by NMR | 70±2% |
| ε-caprolactone by NMR | 30±2% |
| Viscosity (0.5% in CHCl3 at 30°C) | Between 0.90-1.20 dL/g |
| Residual monomer L-Lactide | ≤ 0.5 % |
| Residual monomer ε-caprolactone | ≤ 0.5 % |
| Residual solvent acetone | ≤ 0.1 % |
| Residual solvent toluene | ≤ 890 PPM |
| Total Residual solvent | ≤ 1000 PPM |
| Acid number | ≤6 mg KOH/g |
| Heavy metal | ≤ 10 PPM |
| Tin | ≤ 200 PPM |
| Sulphated Ash | ≤ 0.1 % |
| TAMC | ≤ 2000 CFU/g |
| TYMC | ≤ 200 CFU/g |
| Bacterial Endotoxins | ≤ 2000 EU/g |
| Self life | 2 Years |
| See also: | PLCL |