Poly(L-lactide-co-ε-caprolactone) | PLCL | CAS No : 65408-67-5


Poly(L-lactide-co-ε-caprolactone) | PLCL 70:30   is an Ester terminated Medical Grade copolymer of L-lactide and ε-caprolactone with an inherent viscosity midpoint of 1.2 dl/g.


Product Description

CAS Number65408-67-5
Systematic Name(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione, polymer with 2-oxepanone, PLCL
Molecular Formula[(C6H8O4)x(C4H4O4)y]y
EPA Registry Name L-lactide/Caprolactone copolymer
Substance TypePLCL 70:30 | L10012A | Inherent Viscosity : 1.2 - 1.8 dL/g | Ester terminated
Biodegradable Polymer, Excipient, Non-Active pharmaceutical ingredient, Nanoparticles.
ApplicationsBiodegradable, biocompatible, and bioresorbable copolymer composed of L-Lactide and ε-Caprolactone. This semi-crystalline material has been used in the fabrication of research medical devices and research tissue engineering solutions, such as orthopedic or soft tissue fixation devices. Degradation of these materials has been thoroughly studied and has been shown to be safely resorbed by the body after implantation. Modification of molecular weight and polymer composition allows for control of the degradation rate and mechanical stability of the polymer.



Appearance White to light tan
FT NMR (PROTON) Should comply
Lactide by NMR 70±2%
ε-caprolactone by NMR 30±2%
Viscosity (0.5% in CHCl3 at 30°C) Between 0.90-1.20 dL/g
Residual monomer L-Lactide ≤ 0.5 %
Residual monomer ε-caprolactone ≤ 0.5 %
Residual solvent acetone ≤ 0.1 %
Residual solvent toluene ≤ 890 PPM
Total Residual solvent ≤ 1000 PPM
Acid number ≤6 mg KOH/g
Heavy metal ≤ 10 PPM
Tin ≤ 200 PPM
Sulphated Ash ≤ 0.1 %
TAMC ≤ 2000 CFU/g
TYMC ≤ 200 CFU/g
Bacterial Endotoxins ≤ 2000 EU/g
Self life 2 Years
See also:PLCL