PLCL 70:30 | LCL705

PLCL 70:30 | LCL705, Poly(L-lactide-co-ε-caprolactone) | is an Ester terminated Medical Grade copolymer of L-lactide and ε-caprolactone with an inherent viscosity midpoint of 1.2 dl/g. Biodegradable, biocompatible, and bioresorbable copolymer composed of L-Lactide and ε-Caprolactone. This semi-crystalline material has been used in the fabrication of research medical devices and research tissue engineering solutions, such as orthopedic or soft tissue fixation devices. Degradation of these materials has been thoroughly studied and has been shown to be safely resorbed by the body after implantation. Modification of molecular weight and polymer composition allows for control of the degradation rate and mechanical stability of the polymer.

CAS Number:
65408-67-5

Manufacturing Process:
Ring-Opening

Molecular Formula:
[(C6H8O4)x(C4H4O4)y]y

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Additional information

Synonym(s)

(3S-cis)-3, 4-Dioxane-2, 5-dione copolymer, 6-dimethyl-1, PLCL, polymer with 2-oxepanone

Substance Type

Biodegradable Polymer, Excipient, Nanoparticles, Non-Active pharmaceutical ingredient, PLCL 70:30, Inherent Viscosity: 0.90 – 1.20 dL/g

EPA Registry Name

L-lactide/Caprolactone copolymer

Appearance

FT NMR (PROTON)

Lactide by NMR

ε-caprolactone by NMR

Viscosity (0.5% in CHCl3 at 30°C)

Residual monomer L-Lactide

Residual monomer ε-caprolactone

Residual solvent acetone

Residual solvent toluene

Heavy metal

Tin

Sulphated Ash

TAMC

TYMC

Bacterial Endotoxins

Molecular Weight

~120,000 da

Ratio

l-lactide:caprolactone (70:30)

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