Block Copolymers

PEG Block Copolymers with PLGA, PLA, and PCL

Introduction
PEG (Polyethylene Glycol) block copolymers are versatile materials combining PEG with various other polymers like PLGA (Poly(lactic-co-glycolic acid)), PLA (Polylactic Acid), and PCL (Polycaprolactone). These copolymers leverage the unique properties of PEG to enhance the performance of the other polymer components. They are utilized in a broad range of applications due to their biocompatibility, biodegradability, and ability to modify drug release profiles.

1. PEG-PLGA Block Copolymers

Overview
PEG-PLGA copolymers combine PEG’s hydrophilicity with PLGA’s biodegradability. This combination is highly effective in biomedical applications.

Key Applications

  • Drug Delivery Systems: Formulation of nanoparticles, micelles, and hydrogels for controlled and targeted drug delivery.
  • Tissue Engineering: Development of scaffolds for tissue repair and regeneration.
  • Medical Devices: Creation of bioresorbable implants, stents, and sutures.
  • Cancer Therapy: Design of nanocarriers for targeted delivery of chemotherapeutic agents.

Advantages

  • Enhanced solubility and stability of hydrophobic drugs.
  • Controlled and sustained release profiles.
  • Biodegradable and biocompatible.

2. PEG-PLA Block Copolymers

Overview
PEG-PLA copolymers are known for their micelle-forming abilities and suitability for drug delivery and tissue engineering.

Key Applications

  • Drug Delivery Systems: Micelles and nanoparticles for the delivery of hydrophobic drugs.
  • Tissue Engineering: Scaffolds and hydrogels for regenerative medicine.
  • Medical Devices: Biodegradable sutures and implants.
  • Vaccines and Therapeutics: Carriers for vaccines and protein therapeutics.

Advantages

  • Improved bioavailability and controlled release of drugs.
  • Supports cellular activities and degrades into non-toxic byproducts.
  • Promotes natural healing processes.

3. PEG-PCL Block Copolymers

Overview
PEG-PCL copolymers are valued for their mechanical properties, biodegradability, and application versatility.

Key Applications

  • Drug Delivery Systems: Nanoparticles, micelles, and hydrogels for prolonged drug release.
  • Tissue Engineering: Scaffolds for bone and cartilage regeneration.
  • Medical Devices: Biodegradable stents, sutures, and wound dressings.
  • Industrial Applications: Development of biodegradable plastics and packaging materials.

Advantages

  • Prolonged drug release and enhanced delivery of hydrophobic drugs.
  • Supports tissue regeneration and reduces the need for surgical intervention.
  • Environmentally friendly alternatives to conventional plastics.

 

Showing 1–9 of 55 results

  • Product ID
    Description
    SDS
    Detail
    Product ID
    CL1001MP1
    Description
    mPEG Terminated, Mw PCL (Mw) : ~10,000 da, mPEG (Mw) : ~1500 da
    Detail
    VIEW
  • Product ID
    CL1001MP4
    Description
    mPEG Terminated, Mw PCL (Mw) : ~10,000 da, mPEG (Mw) : ~4000 da
    Detail
    VIEW
  • Product ID
    CL1001P1
    Description
    PEG Terminated, Mw PCL (Mw) : ~10,000 da, PEG (Mw) : ~1500 da
    SDS
    Detail
    VIEW
  • Product ID
    CL1001P4
    Description
    PEG Terminated, Mw PCL (Mw) : ~10,000 da, PEG (Mw) : ~4,000 da
    SDS
    Detail
    VIEW
  • Product ID
    CL1005MP1
    Description
    mPEG Terminated, Mw PCL (Mw) : ~50,000 da, mPEG (Mw) : ~1500 da
    Detail
    VIEW
  • Product ID
    CL1005MP4
    Description
    mPEG Terminated, Mw PCL (Mw) : ~50,000 da, mPEG (Mw) : ~4,000 da
    Detail
    VIEW
  • Product ID
    CL1005P1
    Description
    PEG Terminated, Mw PCL (Mw) : ~50,000 da, PEG (Mw) : ~1500 da
    SDS
    Detail
    VIEW
  • Product ID
    CL1005P4
    Description
    PEG Terminated, Mw PCL (Mw) : ~50,000 da, PEG (Mw) : ~4000 da
    SDS
    Detail
    VIEW
  • Product ID
    DL1001MP1
    Description
    mPEG Terminated, Mw DL-PLA (Mw) : ~10,000 da, m-PEG (Mw) : ~1500 da
    Detail
    VIEW