The hydrogel polymer is an application-tailored PLGA-PEG-PLGA triblock polymer.
The polymer molecule exhibits a hydrophilic core region and hydrophilic ends. An aqueous solution of this polymer is reverse thermosensitive, meaning it is fluid and injectable at room temperature and will rapidly form a hydrogel at body temperature (e.g. after subcutaneous injection).
The polymer is biodegradable due to the instability of ester bonds in the aqueous physiological environment. This process continues at a slow rate and will eliminate the hydrogel from the body in several weeks in a non-toxic way.